A COMPOSITION FOR TREATING STROKE COMPRISING CARBOXYLATE DERIVATIVE

摘要

This invention relates to carboxylate derivatives such as Sodium pyruvate for the treatment of stroke. The abovementioned carboxylate derivatives such as Sodium pyruvate show temporal therapeutic effect in the rat stroke model caused by temporal or permanent middle cerebral artery occlusion. Furthermore, in the long term, it can also reduce the area of cerebral infarction compared to the control group. It also has other excellent long-term effects such as reduced behavioral changes and less weight losses .