发明名称 |
Modified transferrin fusion proteins comprising duplicate transferrin amino or carboxy terminal domains |
摘要 |
Fusion proteins of transferrin and other therapeutic moieties with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor.
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申请公布号 |
US2006130158(A1) |
申请公布日期 |
2006.06.15 |
申请号 |
US20030515324 |
申请日期 |
2003.08.28 |
申请人 |
TURNER ANDREW J;SADEGHI HOMAYOUN |
发明人 |
TURNER ANDREW J.;SADEGHI HOMAYOUN |
分类号 |
A01K67/027;A61K38/00;A61K38/40;A61K47/48;C07H21/04;C07K7/06;C07K7/08;C07K14/705;C07K14/79;C12N1/18;C12N15/74;C12P21/04 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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