发明名称 Radioactively labelled amino acid analogues, their preparation and use
摘要 The present invention relates to Halogenated amino acid analogues for use in diagnosis, which compounds have the genera formula (I) wherein: R is (C<SUB>1</SUB>-C<SUB>6</SUB>) alkyl optionally substituted with thioether or ether oxygen atom when n=0, or a substituted aromatic or heteraromatic ring when n=1-6; and m=0 or 1; and X is a halogen atom. The invention further relates to precursor compounds for these analogues, to a method of preparing these analogues, to a pharmaceutical composition comprising these analogues and to the use of these analogues and compositions in the diagnosis of cancer.
申请公布号 US2006127306(A1) 申请公布日期 2006.06.15
申请号 US20030523184 申请日期 2003.08.01
申请人 MERTENS JOHN J 发明人 MERTENS JOHN J.
分类号 A61K51/00;A61K31/195;A61K49/04;A61K49/10;A61K51/04;A61P35/00;C07D213/55 主分类号 A61K51/00
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