1,2,4-OXADIAZOLE DERIVATIVES AND USE THEREOF AS ANTAGONISTS AT METABOTROPIC GLUTAMATE RECEPTORS

摘要

Compound of formula (?) wherein X, Y and ? are independently selected from the group consisting of N, O, S, C and CO wherein at least one of X, Y and ? is a heteroatom; Ar1 and Ar2 are independently selected from the group consisting of a heterocyclic or fused heterocyclic moiety and an aromatic moiety, act as antagonist at metabotropic glutamate receptors, and are useful for treating neurological diseases and disorders.