发明名称 YEAST-TYPE GROWTH INDUCING AGENT OF DIMORPHIC FUNGUS
摘要 PROBLEM TO BE SOLVED: To provide a yeast-type growth inducing agent of a dimorphic fungus, having high safety and capable of being expected to have an enough effect of improving various symptoms of fungal infections. SOLUTION: This yeast-type growth inducing agent of the dimorphic fungus contains at least one kind selected from a chitosan oligosaccharide, a reduction product of the chitosan oligosaccharide, a chitin oligosaccharide, a reduction product of the chitin oligosaccharide, glucuronic acid, glucosaminitol, lactosylamine, galactosyllactosamine, and salts thereof in an effective amount, so that the agent inhibits mycelium-type growth of the dimorphic fungus and induces yeast-type growth thereof. Thus, the various symptoms of the fungal infections caused by the mycelium-type growth of the dimorphic fungus exhibiting dimorphism are alleviated and improved. It is preferable that the oligosaccharides and the reduction products of the oligosaccharides each have a saccharide polymerization degree of 2 to 8. Further, the agent alleviates and improves the various symptoms of candidiasis, when the dimorphic fungus comprises a Candida fungus, especially Candida albicans, which is a causative fungus of the candidiasis. COPYRIGHT: (C)2006,JPO&NCIPI
申请公布号 JP2006151893(A) 申请公布日期 2006.06.15
申请号 JP20040346462 申请日期 2004.11.30
申请人 YAIZU SUISANKAGAKU INDUSTRY CO LTD 发明人 MATSUMOTO TATSUJI;MIKAMI TAKESHI;WATABE TOSHIHIKO;OGASAWARA AYAKO;MATAHIRA YOSHIHARU;MISAWA YOSHITOMO
分类号 A61K31/7008;A61K31/7012;A61K31/722;A61P31/10;C07H5/04;C07H7/033;C08B37/08;C12N1/16 主分类号 A61K31/7008
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