Process for the preparation of alkynediols

摘要

Alkyne diol preparation from a carbonyl compound and acetylene uses an alkali metal salt prepared in situ as an alcoholate a catalyst. Preparation of alkyne diol of formula (I)comprises reacting a carbonyl compound of formula (II) with acetylene in the prese of an alkali metal salt as catalyst and a polar aprotic solvent. R<1>R<2>C(OH)-C IDENTICAL C-C(OH)R<1>R<2> (I) R<1>-C(=O)-R<2> (II) R<1> and R<2> = H or 1-20C hydrocarbon optionally substituted by 1-6C alkyl and/or halogen and/or interrupted by halogen and/or containing a CC double or triple bond.