发明名称 |
BRONCHORELAXING COMPOUNDS |
摘要 |
<p>A compound of the general formula (I) including its pharmaceutically acceptable acid addition salts formula (I) wherein A is CHR9, wherein R9 is H, C1-C6< >alkyl;n is 1-3; B is CHR10, wherein R10 is H, C1-C6 alkyl; m is 1 or 2; D is O or S; E is CR11R12 or NR13, wherein R11 and R12 are, independent of each other, H or C1-C6 alkyl, R13 is H or C1-C6 alkyl; F is C1-C18 alkyl or R4-R7 cycloalkyl, which may be mono- or di-unsaturated and/or substituted, is useful in treating and preventing pulmonary disease characterized by bronchoconstriction; also disclosed is a pharmaceutical composition comprising the compound of formula (I), a pharmaceutical carrier and, optionally, an anti-asthmatic, a method for its manufacture, and a method for treating or preventing such disease.</p> |
申请公布号 |
WO2005070887(A1) |
申请公布日期 |
2005.08.04 |
申请号 |
WO2005SE00062 |
申请日期 |
2005.01.21 |
申请人 |
RESPIRATORIUS AB;SKOGVALL, STAFFAN;DALENCE GUZMAN, MARIA;BJOERK, HENRIK;BERGLUND, MAGNUS;STERNER, OLOF |
发明人 |
SKOGVALL, STAFFAN;DALENCE GUZMAN, MARIA;BJOERK, HENRIK;BERGLUND, MAGNUS;STERNER, OLOF |
分类号 |
C07D217/06;C07D223/16;(IPC1-7):C07D209/44;A61P11/06;A61K31/403;A61K31/472;A61K31/55 |
主分类号 |
C07D217/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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