| 摘要 |
A compound selected from those of formula (I): wherein: B<SUB>1</SUB>, B<SUB>2 </SUB>represent carbon or nitrogen, X, Y, X<SUB>1 </SUB>and Y<SUB>1 </SUB>represent a group selected from hydrogen, halogen, hydroxy, alkoxy, nitro, cyano, trihaloalkyl and NR<SUB>a</SUB>R<SUB>b </SUB>wherein R<SUB>a </SUB>and R<SUB>b </SUB>are as defined in the description, R<SUB>1 </SUB>represents hydrogen or alkyl, R<SUB>2 </SUB>represents a group selected from hydrogen, alkyl, -OR''<SUB>a</SUB>, -NR'<SUB>a</SUB>R'<SUB>b</SUB>, -O-T<SUB>a</SUB>-OR''<SUB>a</SUB>, -NR''<SUB>a</SUB>-T<SUB>a</SUB>-NR'<SUB>a</SUB>R'<SUB>b</SUB>, NR''<SUB>a</SUB>-C(O)-T<SUB>a</SUB>H, -O-C(O)-T<SUB>a</SUB>H, -O-T<SUB>a</SUB>-NR<SUB>a</SUB>'R<SUB>b</SUB>', -NR''<SUB>a</SUB>-T<SUB>a</SUB>-OR''<SUB>a</SUB>, -NR''<SUB>a</SUB>-T<SUB>a</SUB>-CO<SUB>2</SUB>R''<SUB>a </SUB>and -NR''<SUB>a</SUB>-C(O)-T<SUB>a</SUB>-NR'<SUB>a</SUB>R'<SUB>b </SUB>wherein R'<SUB>a</SUB>, R'<SUB>b</SUB>, R''<SUB>a </SUB>and T<SUB>a </SUB>are as defined in the description, R<SUB>3</SUB>, R<SUB>4 </SUB>represent hydrogen or alkyl, A represents a group of formula -CH(R<SUB>5</SUB>)-CH(R<SUB>6</SUB>)-, -CH-C(R<SUB>7</SUB>)-, -C(R<SUB>7</SUB>)-CH-, -C(O)-CH(R<SUB>8</SUB>)- or -CH(R<SUB>8</SUB>)-C(O)- wherein R<SUB>5</SUB>, R<SUB>6</SUB>, R<SUB>7 </SUB>and R<SUB>8 </SUB>are as defined in the description, its isomers, N-oxides, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful in the treatment of cancer.
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