CONFORMATIONALLY CONSTRAINED SMAC MIMETICS AND THE USES THEREOF
摘要
The invention relates to conformationally constrained mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.
申请公布号
WO2005069894(A2)
申请公布日期
2005.08.04
申请号
WO2005US01406
申请日期
2005.01.18
申请人
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;WANG, SHAOMENG;SUM, HAIYING;NIKOLOVSKA-COLESKA, ZANETA;YANG, CHAO-YIO;XU, LIANG