发明名称 CONFORMATIONALLY CONSTRAINED SMAC MIMETICS AND THE USES THEREOF
摘要 The invention relates to conformationally constrained mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.
申请公布号 WO2005069894(A2) 申请公布日期 2005.08.04
申请号 WO2005US01406 申请日期 2005.01.18
申请人 THE REGENTS OF THE UNIVERSITY OF MICHIGAN;WANG, SHAOMENG;SUM, HAIYING;NIKOLOVSKA-COLESKA, ZANETA;YANG, CHAO-YIO;XU, LIANG 发明人 WANG, SHAOMENG;SUM, HAIYING;NIKOLOVSKA-COLESKA, ZANETA;YANG, CHAO-YIO;XU, LIANG
分类号 A61K31/395;A61K31/407;A61K31/4353;A61K31/437;A61K31/4375;A61K31/55;A61P35/00;C07D455/02;C07D471/04;C07D487/04;C07K5/08;C07K5/083 主分类号 A61K31/395
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