BIOSENSORS UTILIZING DENDRIMER-IMMOBILIZED LIGANDS AND THEIR USE THEREOF
摘要
The present invention is directed to methods and compositions useful as biosensors that specifically interact with various pathogens and other target analytes. The biosensor itself, comprises functionalized dendritic tethers derivatized for attachment to a variety of surfaces as self-assembled monolayers (SAMs) as well as attached binding moieties (sometimes referred to as capture binding ligands). Accordingly, the present invention provides compositions comprising supports comprising surfaces to which the binding moieties (e.g. antibodies) are attached for the detection of target analytes (e.g. pathogens) as well as methods and compositions relating to the attachment of such binding moieties.
申请公布号
WO2005016115(A2)
申请公布日期
2005.02.24
申请号
WO2004US01961
申请日期
2004.01.23
申请人
MONTANA STATE UNIVERSITY;SPANGLER, BRENDA, D.;SPANGLER, CHARLES, W.