发明名称 |
COMPOSITIONS AND METHODS FOR REDUCING THE RISK OF EPILEPTIC OCCURRENCE AND/OR FOR TREATMENT OF SEIZURE DISORDERS |
摘要 |
The present invention relates to compounds and compositions useful for reducing the risk of epileptic occurrences and/or for alleviating epileptic phenomena in patients. In accordance with the invention, the compounds and compositions have at least the following two components: a) vitamin B6-based component selected from pyridoxal, pyridoxamine, pyridoxine, their pharmaceutically acceptable functional derivatives and salts; and b) at leas t one antiepileptic drug (AED) or anticonvulsive, neuroprotective drug or nootrope compound or moiety. The invention further relates to methods for preventing epileptic episodes and for alleviating epileptic episodes, as wel l as methods for reducing side effects of antiepileptic drugs.
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申请公布号 |
CA2535483(A1) |
申请公布日期 |
2005.02.24 |
申请号 |
CA20042535483 |
申请日期 |
2004.08.12 |
申请人 |
ADVANCED NEUROPROTECTIVE SYSTEMS LTD.;D-PHARM LTD. |
发明人 |
SHAPIRO, ISRAEL;VINNIKOVA, MARINA;SHTEIMAN, VITALY;DOLINA, SVETLANA |
分类号 |
C07D213/02;A61K;A61K31/44;A61P25/08;C07D |
主分类号 |
C07D213/02 |
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