发明名称 |
Methods to treat diabetes and related conditions based on polymorphisms in the tcf-1 gene |
摘要 |
This invention relates to the use of the novel association between the 483 A>G single nucleotide polymorphism of the TCF1 gene and the clinical response to glycemic control agents, such as DPPIV inhibitors, in patients with disorders of glycemic control, especially diabetes and impaired glucose metabolism. This invention provides methods to classify patients for treatment and/or for optimization of clinical studies and to treat patients based on this association.
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申请公布号 |
US2005042614(A1) |
申请公布日期 |
2005.02.24 |
申请号 |
US20040493885 |
申请日期 |
2004.10.15 |
申请人 |
HUGHES THOMAS EDWARD;LAVEDAN CHRISTIAN NICOLAS;POLYMEROPOULOS MILHAEL HRISTOS |
发明人 |
HUGHES THOMAS EDWARD;LAVEDAN CHRISTIAN NICOLAS;POLYMEROPOULOS MILHAEL HRISTOS |
分类号 |
C12N15/09;A61K31/40;A61K31/4439;A61K38/55;A61K49/00;A61P3/04;A61P3/06;A61P3/08;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P19/06;A61P27/02;A61P35/00;A61P43/00;C07D207/16;C07D401/12;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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