发明名称 |
Nucleotide vector, composition containing such vector and vaccine for immunization against hepatitis |
摘要 |
Nucleotide vector comprising at least one gene or one complementary DNA coding for at least a portion of a virus, and a promoter providing for the expression of such gene in muscle cells. The gene may be the S gene of the hepatitis B virus. A vaccine preparation containing said bare DNA is injected into the host previously treated with a substance capable of inducing a coagulating necrosis of the muscle fibres.
|
申请公布号 |
US2005042203(A1) |
申请公布日期 |
2005.02.24 |
申请号 |
US20030644267 |
申请日期 |
2003.08.20 |
申请人 |
INSTITUT PASTEUR;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;UNIVERSITE D'OTTAWA |
发明人 |
DAVIS HEATHER LYNN;WHALEN ROBERT GERALD;MICHEL MARIE-LOUISE |
分类号 |
A61K39/00;A61K39/29;A61K48/00;C07K14/02;(IPC1-7):A61K48/00;C12N15/86 |
主分类号 |
A61K39/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|