MELKS AS MODIFIERS OF THE RAC PATHWAY AND METHODS OF USE
摘要
Human MELK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of MELK are provided.
申请公布号
WO2005016279(A2)
申请公布日期
2005.02.24
申请号
WO2004US26231
申请日期
2004.08.12
申请人
EXELIXIS, INC.;KADYK, LISA;FRANCIS, GEORGE, ROSS;HEUER, TIMOTHY, S.;LICKTEIG, KIM
发明人
KADYK, LISA;FRANCIS, GEORGE, ROSS;HEUER, TIMOTHY, S.;LICKTEIG, KIM