发明名称 |
REDUCING PROTEIN A LEACHING DURING PROTEIN A AFFINITY CHROMATOGRAPHY |
摘要 |
A method for reducing leaching of protein A during protein A affinity chromatography is described which involves reducing temperature or pH of, or by adding one or more protease inhibitors to, a composition that is subjecte d to protein A affinity chromatography. |
申请公布号 |
CA2531595(A1) |
申请公布日期 |
2005.02.24 |
申请号 |
CA20042531595 |
申请日期 |
2004.06.24 |
申请人 |
GENENTECH, INC. |
发明人 |
MCDONALD, PAUL J.;LAVERDIERE, AMY;FAHRNER, ROBERT L.;O'LEARY, RHONA M. |
分类号 |
C07K16/06 |
主分类号 |
C07K16/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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