CLONING VECTORS CONTAINING SELECTABLE GENETIC MARKERS FOR USE IN STREPTOMYCES AND RELATED ORGANISMS

摘要

The present invention discloses novel recombinant DNA cloning vectors for use in Streptomyces and related organisms. These novel cloning vectors comprise a) a functional origin of replication-con-taining restriction fragment of plasmid pFJ301, and b) one or more DNA segments that convey resistance to at least one antibiotic or colorimetric selectivity when transformed into a sensitive, restrictionless E. coli or Streptomyces host cell that is susceptible to transformation, cell division, and culture.