发明名称 Anti-inflammatory carboxy pregnane derivatives
摘要 Compounds of the formula: <IMAGE> wherein one X is COOR, CH2COOR, CH(COOR)2, CONHR, CH2CONHR, or CN remaining X's are H, F, CH3, OH, COOR, CH2COOR, CH(COOR)2, CONHR, CH2CONHR, or CN; Y is <IMAGE> +TR <IMAGE> R is H, alkyl of 1-5 carbon atoms, or benzyl; R1 is CH2OR3, COOR, or CONHR; R2 is H, OR3, or BR; R3 is H, COR4, or tetrahydropyranyl; R4 is alkyl of 1-5 carbon atoms or benzyl; R5 is H or COR4; represents a single or double bond; represents alpha -position, beta -position, or a mixture of alpha - and beta -positions; and --- represents alpha -position; and methods for preparing the same.
申请公布号 US4762919(A) 申请公布日期 1988.08.09
申请号 US19860828460 申请日期 1986.02.12
申请人 FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY 发明人 LEE, HENRY J.
分类号 C07J1/00;C07J5/00;C07J7/00;C07J13/00;C07J17/00;C07J21/00;C07J41/00;C07J71/00;(IPC1-7):C07J21/00 主分类号 C07J1/00
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