PREPARATION OF INDOLINE-2-ONE DERIVATIVES

摘要

A process which comprises reductive cyclisation of a compound of structure (II) in which n is 1 to 3 and X is a group displaceable by amine in the presence of at least two equivalents of anhydrous iron (III) chloride and at least two equivalents of an acetyl halide and a solvent to form a compound of structure (III) in which X and n are as hereinabove defined, Z is halogen. f