发明名称 OLIGOPEPTIDES WITH CYCLIC PROLINE-ANALOGOUS AMINO ACIDS
摘要 The invention relates to compounds of the formula I <IMAGE> in which A is an optionally substituted radical from the series comprising alkyl, acyl, cycloalkyl, aryl and heteroaryl; Cyc is an optionally substituted heterocyclic carbonyl compound; D is NH, NCH3, O or CH2; E is CHOH, CO, SO or optionally N-substituted C=NH; F is O, NH, NCH3 or a bond; R<4> is an optionally substituted radical from the series comprising alkyl, cycloalkyl, aryl and heteroaryl; and R<8> is hydrogen or optionally substituted alkyl, process for the preparation thereof and the use thereof as inhibitors of prolyl hydroxylase.
申请公布号 ZA8904178(B) 申请公布日期 1990.02.28
申请号 ZA19890004178 申请日期 1989.06.02
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 STEPHEN HENKE;DIETRICH BROCKS;VOLKMAR GUENZLER-PUKALL;KARI IIKKA KIVIRIKKO;RAILI MIRJA HELENA MYLLYLAE
分类号 C07D233/02;A61K38/00;A61K38/55;A61P1/16;A61P9/10;A61P11/00;A61P17/00;A61P35/00;A61P37/06;C07D231/04;C07D263/04;C07D263/06;C07D265/30;C07D277/06;C07K1/113;C07K5/06;C07K5/065;C07K5/08;C07K5/087 主分类号 C07D233/02
代理机构 代理人
主权项
地址