发明名称 OLIGOSACCHARIDE-CONTAINING INHIBITORS OF ENDOTHELIAL CELL GROWTH AND ANGIOGENESIS
摘要 Novel fractions comprising oligosaccharides having 6 to 8 saccharide units and molecular weights between 1,000 and 2,000 and a sulfur content of less than 9 weight percent, are obtained by depolymerizing heparin or heparan sulfate and fractionating the digest by size and charge. These fractions inhibit capillary endothelial cell proliferation in vitro and are useful in the in vivo inhibition of angiogenesis.
申请公布号 AU5445290(A) 申请公布日期 1990.11.16
申请号 AU19900054452 申请日期 1990.04.24
申请人 KABIVITRUM AB 发明人 KARIN HELENA LOUISE BERGENDAHL;ROLF ARNE JOHANSSON;JAN CHRISTER MATTSSON;CARL MAGNUS ERIK SVAHN;MOSES JUDAH FOLKMAN;JUDITH SUDHALTER;PATRICIA D'AMORE
分类号 C07H11/00;C08B37/00 主分类号 C07H11/00
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