| 发明名称 |
SURAMIN TYPE COMPOUNDS AND ANGIOSTATIC STEROIDS TO INHIBIT ANGIOGENESIS |
| 摘要 |
The invention is a method of treating angiogenesis in a warm blooded mammal who is in need of such treatment which comprises administration of an angiogenic inhibiting amount of a combination of a suramin-type compound and an angiostatic steroid. Angiostatic steroids include the known 20-substituted steroids of formula (I), 21-hydroxy steroids of formula (II), C11-functionalized steroids of formula (III) as well as the novel DELTA <9(11)>-etianic esters of formula (IV), as well as various individual known steroids. |
| 申请公布号 |
WO9015816(A1) |
申请公布日期 |
1990.12.27 |
| 申请号 |
WO1990US02673 |
申请日期 |
1990.05.17 |
| 申请人 |
THE UPJOHN COMPANY |
发明人 |
ARISTOFF, PAUL, A.;MITCHELL, MARK, A.;WILKS, JOHN, W. |
| 分类号 |
A61K31/185;A61K31/495;A61K31/565;A61K31/57;A61K31/66;A61P3/02;A61P3/08;A61P9/10;A61P9/14;A61P13/02;A61P15/00;A61P17/00;A61P27/02;A61P33/00;A61P35/00;C07J3/00;C07J31/00;C07J43/00 |
主分类号 |
A61K31/185 |
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