发明名称 |
NEW PIPERIDINE DERIVATIVES AS ANTIHISTAMINICS |
摘要 |
New antihistaminic piperidine derivatives of general structural formula I are prepared by reacting 4-piperidinealkylamines with carboxylic acids or their active derivatives, such as lower-alkyl esters or the acid chlorides. The obtained new piperidine carboxamide compounds show potent antihistaminic activity as specific antagonists of histamine H1-receptors. <CHEM> r |
申请公布号 |
ZA9001442(B) |
申请公布日期 |
1990.12.28 |
申请号 |
ZA19900001442 |
申请日期 |
1990.02.26 |
申请人 |
FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMECEUTICOS S.A. (FAES) |
发明人 |
AURELIO ORJALES VENERO;ANTONIO TOLEDO AVELLO |
分类号 |
C07D211/32;A61K31/4427;A61K31/445;A61K31/4468;A61P43/00;C07D401/12;C07D417/12 |
主分类号 |
C07D211/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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