发明名称 NOVEL DIHYDRO-1,2 OXO-2 QUINOXALINE DERIVATES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
摘要 Novel dihydro-1,2 oxo-2 quinoxaline derivates corresponding to general formula (I) in which R represents a hydrogen or halogen atom; R1 represents a hydrogen atom or C1-C4 alkyl radical, linear or branched; R2 represents: a hydrogen atom, a C(O)R4 radical where R4 is C1-C4 alkyl group, linear or branched, a C(O)NHR4 radical where R5 is C1-C4 alkyl group linear or branched, or a phenyl group; A represents C1-C4 alkylene chain; R3 represents a hydrogen atom, C1-C4 alkyl radical, C3-C6 cycloalkyl radical, an alkynyl, nitril, hydroxyl, carboxamido, pyridyl, phenyl group or a phenyl substituted by a halogen atom, C1-C4 alkyl group, C1-C4 alkoxy group, or a nitro group; an alkenyl radical of formula ( alpha ) where R6, R7 can, independently of each other, be a hydrogen atom, C1-C4 alkyl group, a phenyl group, or an alkoxycarbonyl group; a radical of the formula -OC(O)R8, where R8 represents C1-C4 alkyl radical; a radical of the formula -OC(O)NHR9, where R9 represents C1-C4 alkyl radical, linear or branched, or a phenyl group; n can take values from 2 to 4, as well as the organic or mineral salts of said molecules which are therapeutically acceptable.
申请公布号 WO9105772(A1) 申请公布日期 1991.05.02
申请号 WO1990FR00752 申请日期 1990.10.17
申请人 PIERRE FABRE MEDICAMENT 发明人 PITET, GUY;FAURE, CHRISTIAN;COURET, FRANCOISE;BIGG, DENNIS;TARAYRE, JEAN-PIERRE
分类号 A61K31/495;A61P11/08;C07D241/44;C07D401/06 主分类号 A61K31/495
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