摘要 |
<p>The present invention relates to novel Spergualin-related compounds represented by the general formula [I] <CHEM> R2 is a residue obtained by removing, from an amino acid or peptide, the hydroxyl group of the carboxyl group and, when R1 is a group other than -H, R2 is same as R1 , or a pharmacologically acceptable salt thereof. Said compounds or salts thereof have an immuno-modulating action. The invention further relates to pharmaceutical formulations having an immuno-modulating activity which contain such Spergualin-related compounds and a process for the manufacture of these compounds and preparations.</p> |
申请人 |
MICROBIAL CHEMISTRY RESEARCH FOUNDATION, TOKIO/TOKYO, JP |
发明人 |
UMEZAWA, HAMAO, DECEASED, JP;TAKEUCHI, TOMIO, 5-CHOME SHINAGAWA-KU TOKYO, JP;SAINO, TETSUSHI, YONO-CITY SAITAMA PREFECTURE, JP;YOSHIDA, MASAO, HIGASHI-KURUME-CITY TOKYO, JP;TAKAHASHI, KATSUTOSHI, KITA-KU TOKYO, JP;NAKAMURA, TERUYA, KUSATSU-CITY SHIGA PREFECTURE, JP |