New potassium-magnesium L-ascorbate-2-phosphate - recovered as stable, easily processed crystals from ascorbic acid phosphorylation mixt.

摘要

K-Mg L-ascorbate-2-phosphate (I) is a new cpd. Pref., it has K:Mg atom ratio 1 +/- 0.3 : 1 +/- 0.15. The salt is prepd. by treating aq. soln. of K L-ascorbate-2-phosphate (III) with a medium-acidity cation exchanger which loses its exchange capacity at pH 2-0.5 to produce a soln. of mono-K salt. This is treated with MgO, Mg(OH)2 or MgCO3 to about pH7 and the soln. opt. treated with MeOH or acetone to ppte. (I). USE/ADVANTAGE - Conversion to (I) is used to recover L-ascorbic acid-2-phosphate (II) from phosphorylation mixt. It is produced free of inorganic salts; in well-crystallisation form which is easy to filter, non-hygroscopic and has little tendency to cake or form dust. The use of a medium-acidity resin produces an eluate which is not strongly acid (so does not decompose the product); MgO consumption and salt discharge are reduced, and regeneration times for the resin are Compared with ascorbic acid itself, (II) is more stable to oxygen, heat and hydrolysis, and has universal bioavailability.