发明名称 |
INHIBITION OF 5-LIPOXYGENASE AND CYCLOOXYGENASE PRODUCTS |
摘要 |
A method of dual inhibition of 5-lipoxygenase pathway mediated diseases and cyclooxygenase pathway mediated diseases in a subject in need thereof which comprises administering to such subject an effective, non-toxic 5-lipoxygenase pathway inhibiting amount or an effective, non-toxic cyclooxygenase pathway inhibiting amount of a diaryl-substituted imidazole fused to a second unsaturated 5 or 6 membered heterocyclic ring containing a nitrogen bridgehead atom wherein said second 5 membered ring also contains a sulfur or oxygen atom or said 6 membered ring may also contain an additional nitrogen atom. |
申请公布号 |
IE911977(A1) |
申请公布日期 |
1991.12.18 |
申请号 |
IE19910001977 |
申请日期 |
1991.06.11 |
申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
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分类号 |
A61K31/435;A61K31/44;A61K31/445;A61K31/505;A61P43/00;C07D471/04;C07D487/04;C07D498/04;C07D513/04 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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