摘要 |
<p>A method is provided for treating patients suffering from or susceptible to bronchoconstriction, particularly for patients suffering from an asthmatic attack which comprises the use of benzothiophene, benzofuran, dihydronaphthalene or indene derivatives represented by formula I <CHEM> wherein each of R<1>, R<2>, R<3> and R<4> is independently H, (1-4C) alkyl, (1-4C) halogen substituted alkyl, OH, (1-4C) alkoxy, (1-4C) halogen substituted alkoxy, NO2, CN, halogen, an unsubstituted or (1-4C) alkyl substituted amino group, or wherein two adjacent groups R<1>, R<2>, R<3> or R<4> together form methylenedioxy; X is S, O or (CH2)m in which m is 1 or 2; R<5> is H or (1-4C) alkyl; R<6> is H, NH2 or (1-4C) alkyl; R<7> is H, (1-4C) alkyl or OR<8> in which R<8> is H, (1-4C) alkyl or (1-8C) acyl; and its pharmaceutically acceptable salts for the prepa ration of a medicament with bronchodilator activity.</p> |