发明名称 NANOCAPSULE-CONTAINING PHARMACEUTICAL COMPOSITIONS AND PROCESS FOR PRODUCTION OF THEM
摘要 Pharmaceutical composition in the form of a colloidal suspension of nanocapsules which comprises an oily phase consisting essentially of an oil containing, in solution, a surface-active agent and, in suspension, nanocapsules having a diameter of less than 500 nanometers, including an aqueous phase consisting essentially of a solution or a suspension of a substance of therapeutic activity, a surface-active agent and optionally ethanol, as well as a process for the preparation of this composition. The walls of the said nanocapsules are formed of a poly(alkyl 2-cyanoacrylate) the alkyl radical of which includes from 1 to 6 carbon atoms. This composition is advantageously suitable for the oral administration of polypeptides and polysaccharides.
申请公布号 HUT67213(A) 申请公布日期 1995.03.28
申请号 HU19940000107 申请日期 1994.01.14
申请人 UCB S. A. 发明人 VRANCKX,HENRI;DEMOUSTIER,MARTINE;DELEERS,MICHEL
分类号 A61K38/28;A61K9/51;A61K31/715;A61K31/727;A61K38/04;A61K38/23;A61K47/32;B01J13/14;B01J13/18;(IPC1-7):A61K9/51 主分类号 A61K38/28
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