发明名称 PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS.
摘要 <p>The present invention is directed to compounds of the structural Formula: wherein: R1 is H or -C1-C3 alkyl; R2 is selected from the group consisting of -H, -C1-C4 alkyl, -C1-C3 alkyl-CF3, phenyl, and pyridinyl; and R3 is selected from the group consisting of -H, -C1-C4 alkyl, -C1-C3 alkyl-O-CH3, -CH2-cyclopropyl, -CH2-C=CH2, -CH2CH2-(2-F-phenyl), and phenyl substituted with from 1 to 2 fluorines; provided that when R1 and R2 are each H, then R3 is selected from the group consisting of -C1-C4 alkyl, -C1-C3 alkyl-O-CH3, -CH2-cyclopropyl, -CH2-C=CH2, -CH2CH2-(2-F-phenyl), and phenyl substituted with from 1 to 2 fluorines; or stereoisomers and pharmaceutically acceptable salts thereof.</p>
申请公布号 MX2009008998(A) 申请公布日期 2009.09.02
申请号 MX20090008998 申请日期 2008.02.12
申请人 ELI LILLY AND COMPANY. 发明人 TIANWEI MA;NATHAN BRYAN MANTLO;LANCE ALLEN PFEIFER;LAURA FREY MICHAEL;FESE MAMBO MOKUBE;CHAHRZAD MONTROSE-RAFIZADEH
分类号 C07D249/12;A61K31/4196;A61K31/4439;A61P3/00;C07D401/06 主分类号 C07D249/12
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