DEVICE FOR THE TRANSDERMAL ADMINISTRATION OF BISOPROLOL.

摘要

A device for the administration of bisoprolol having a support; and a pressure-sensitive adhesive layer containing bisoprolol which is layered on one face of the support; wherein the maximum speed of releasing bisoprolol within 24 hours immediately after the application to the skin is 30 μg/cm2/h or less and the speed of releasing bisoprolol at the point 24 hours after the application to the skin is 10 μg/cm2/h or less. This transdermal administration device shows a relived skin irritation at the application and, in particular, at the peeling and enables the continuous administration of a therapeutically or preventively effective amount of bisoprolol to the living body.