发明名称 CARBOXYLIC ACID DERIVATIVE
摘要 <p>To provide a compound which is usable as a drug, in particular, an insulin secretagogue or a preventive or remedy for a disease in which GPR40 participates such as diabetes or the like. [MEANS FOR SOLVING PROBLEMS] If is found out that a novel carboxylic acid derivative, which is characterized in that a carboxylic acid is bonded via two atoms to a 6-membered monocyclic aromatic ring and this aromatic ring is further bonded via a linker to a nitrogen-containing bicyclic ring, or its salt has an excellent GPR40 agonist activity, Because of showing excellent effects of promoting insulin secretion and lowering blood glucose level, this carboxylic acid derivative is useful as an insulin secretagogue or a preventive or remedy for diabetes.</p>
申请公布号 EP2096109(A1) 申请公布日期 2009.09.02
申请号 EP20070832729 申请日期 2007.11.29
申请人 ASTELLAS PHARMA INC. 发明人 NEGORO, KENJI;OHNUKI, KEI;KUROSAKI, TOSHIO;IWASAKI, FUMIYOSHI;YONETOKU, YASUHIRO;TSUCHIYA, KAZUYUKI;ASAI, NORIO;YOSHIDA, SHIGERU;SOGA, TAKATOSHI;SUZUKI, DAISUKE
分类号 C07D215/14;A61K31/404;A61K31/4184;A61K31/4375;A61K31/4439;A61K31/4523;A61K31/47;A61K31/4706;A61K31/4709;A61K31/496;A61K31/497;A61K31/5377;A61K31/538;A61K31/541;A61P3/10;A61P43/00;C07D209/08;C07D215/26;C07D215/40;C07D215/58 主分类号 C07D215/14
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