摘要 |
A threading intercalator of general formula I: <?in-line-formulae description="In-line Formulae" end="lead"?>IG1-DG-IG2-(DG-IG3)n (I)<?in-line-formulae description="In-line Formulae" end="tail"?> wherein IG1, IG2, and IG3 are the same or different and represent an intercalating group comprising a planar polyaromatic group; wherein DG represents an electrochemical, a chemiluminescent, a catalytic or an electrochemiluminescent detectable group; and wherein n represents 0 or 1. This invention also relates to a process of detecting a double strand nucleic acid molecule using the threading intercalator.
|