发明名称 CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions
摘要 The present invention relates to the CGRP-antagonists of general formula I wherein R1, R2, R3, R4 and X are defined as in claim 1, the tautomers, the isomers, the diastereomers, the enantiomers, the hydrates, mixtures and salts thereof and the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, as well as those compounds of general formula I in which one or more hydrogen atoms are replaced by deuterium, pharmaceutical compositions containing these compounds, the use thereof and processes for the preparation thereof.
申请公布号 US2009186881(A1) 申请公布日期 2009.07.23
申请号 US20090363175 申请日期 2009.01.30
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 MUELLER STEPHAN GEORG;RUDOLF KLAUS;LUSTENBERGER PHILIPP;STENKAMP DIRK;SANTAGOSTINO MARCO;PALEARI FABIO;SCHAENZLE GERHARD;ARNDT KIRSTEN;DOODS HENRI
分类号 A61K31/551;A61K31/496;A61K31/517;A61K31/537;A61P3/00;A61P9/00;A61P29/00;C07D239/72;C07D243/04;C07D265/04;C07D401/14 主分类号 A61K31/551
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