The Invention relates to improved nucleic acid probes and to broad-range primers that are useful in the identification of bacterial species and the diagnosis of bacterial infections. Especially, the invention relates to specific nucleic acid probes that originate from hyper-variable regions situated between the conserved sequences of topoisomerase genes of infection-causing bacteria. The invention also relates to improved broad-range primers originating from the conserved regions of topoisomerase genes. In addition, the invention relates to the use of these improved nucleic acid probes and broad-range primers in the diagnosis of bacterial infections as well as to methods in which these nucleic acid probes and broad-range primers are used.
申请公布号
WO2009090311(A2)
申请公布日期
2009.07.23
申请号
WO2009FI50037
申请日期
2009.01.16
申请人
MOBIDIAG OY;MAEKI, MINNA-MARI;PELLOSNIEMI, JAAKKO;PIIPARINEN, PASI
发明人
MAEKI, MINNA-MARI;PELLOSNIEMI, JAAKKO;PIIPARINEN, PASI