发明名称 METHOD FOR INHIBITING PROLIFERATION OF CANCER CELL, PROLIFERATION INHIBITOR AND SCREENING METHOD
摘要 <P>PROBLEM TO BE SOLVED: To provide an effective and reliable therapeutic method of cancer, to provide a proliferation inhibitor of cancer cells effective for the therapy, and to provide a screening method of a material having proliferation-inhibiting activity of the cancer cells. <P>SOLUTION: The method for inhibiting the proliferation of the cancer cells includes inhibiting the function of ZNF143. The cancer cell proliferation inhibitor contains a material inhibiting the function of ZNF143 such as siRNA specific to ZNF143 as an active ingredient. The therapeutic agent of the cancer, the method for detecting the cancer cells, the agent for diagnosing the cancer, the vector and the transformed cell to which the vector is introduced, and the screening method of the material having the activity for inhibiting the proliferation of the cancer cells with the use of the amount of ZNF143 protein-binding inhibition as a standard, are also provided. <P>COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009159869(A) 申请公布日期 2009.07.23
申请号 JP20070341430 申请日期 2007.12.28
申请人 UNIV OF OCCUPATIONAL & ENVIRONMENTAL HEALTH JAPAN 发明人 KONO KIMITOSHI;IZUMI HIROHITO;SASAKURI YASUYUKI
分类号 C12N15/09;A61K31/7088;A61K31/713;A61K35/76;A61K45/00;A61P35/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12Q1/02;G01N33/15;G01N33/50;G01N33/53;G01N33/574 主分类号 C12N15/09
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