摘要 |
Methods are provided to manipulate phagocytosis of cells, including hematopoietic cells, e.g. circulating hematopoietic cells, bone marrow cells, etc.; and solid tumor cells. In some embodiments of the invention the circulating cells are hematopoietic stem cells, or hematopoietic progenitor cells, particularly in a transplantation context, where protection from phagocytosis is desirable. In other embodiments the circulating cells are leukemia cells, particularly acute myeloid leukemia (AML), where increased phagocytosis is desirable. |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;JAISWAL, SIDDHARTHA;WEISSMAN, IRVING, L.;JAMIESON, CATRIONA, HELEN, M.;MAJETI, RAVINDRA |
发明人 |
JAISWAL, SIDDHARTHA;WEISSMAN, IRVING, L.;JAMIESON, CATRIONA, HELEN, M.;MAJETI, RAVINDRA |