发明名称 |
OLIGONUCLEOTIDES FOR MODULATION OF TARGET RNA ACTIVITY |
摘要 |
The present invention relates to oligonucleotides for modulation of target RNA activity. Thus, the invention provides oligonucleotides that bind to microRNA binding sites of target RNA. The oligonucleotides may activate RNase H or RNAi. In a preferred embodiment, the oligonucleotides prevents a microRNA from binding to itsbinding site of the target RNA and thereby prevent the microRNA from regulating the target RNA. Such oligonucleotides have uses in research and development of new therapeutics. |
申请公布号 |
WO2008151639(A3) |
申请公布日期 |
2009.07.23 |
申请号 |
WO2008DK50141 |
申请日期 |
2008.06.13 |
申请人 |
QUERDENKER APS;MOELLER, THORLEIF |
发明人 |
MOELLER, THORLEIF |
分类号 |
A61K31/7088;A61P31/14;C12N15/113 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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