摘要 |
<p>A bio-heart originating from a biological material, in particular, a blood vessel which provides one-way blood flow, has a thicker myocardial layer, and has an enlarged capacity and an elevated output power. Provided is a substitute heart which comprises a valved blood vessel having been treated to lower the antigenicity and a myocardial cell layer formed therearound. Also provided is a method of constructing a blood vessel-origin bio-heart characterized by comprising connecting the substitute heart constructed above to an intraperitoneal blood vessel in a living body to allow blood flow, wrapping the omental around the outside of the myocardial layer and thus holding the substitute heart that is autonomously beating in the living body.</p> |
申请人 |
JICHI MEDICAL UNIVERSITY;TOKYO WOMEN'S MEDICAL UNIVERSITY;OTSUKA PHARMACEUTICAL FACTORY, INC.;KOBAYASHI, EIJI;KONNO, KENJIRO;OKANO, TERUO;SHIMIZU, TATSUYA;SEKINE, HIDEKAZU |
发明人 |
KOBAYASHI, EIJI;KONNO, KENJIRO;OKANO, TERUO;SHIMIZU, TATSUYA;SEKINE, HIDEKAZU |