| 发明名称 |
Combretastatin A-4 Phosphate Prodrug Mono- and Di- Organic Amine Salts, Mono- and Di- Amino Acid Salts, and Mono- and Di- Amino Acid Ester Salts |
| 摘要 |
Provided herein are novel and useful combretastatin A-4 prodrug salts that increase the solubility of combretastatin A-4, readily regenerate combretastatin A-4 in vivo under normal physiological conditions, and which produce physiologically tolerable products as a result of the regeneration of combretastatin A-4.
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| 申请公布号 |
US2009186857(A1) |
申请公布日期 |
2009.07.23 |
| 申请号 |
US20080265586 |
申请日期 |
2008.11.05 |
| 申请人 |
VENIT JOHN J;DALI MANDAR V;DALI MANISHA M;HUANG YANDE;DAHLHEIM CHARLES E;TEJWANI RAVINDRA W |
发明人 |
VENIT JOHN J.;DALI MANDAR V.;DALI MANISHA M.;HUANG YANDE;DAHLHEIM CHARLES E.;TEJWANI RAVINDRA W. |
| 分类号 |
A61K31/66;C07F9/02;C07F9/12 |
主分类号 |
A61K31/66 |
| 代理机构 |
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