METHOD FOR PRODUCING ADENINE COMPOUND

摘要

Disclosed is a method for producing an adenine compound represented by Formula (4) which is useful as a pharmaceutical product. In the method, a compound represented by Formula (1) is converted into a compound represented by Formula (2) by a debenzylation reaction, and then the thus-obtained compound of Formula (2) is reacted with a compound represented by Formula (3) in the presence of a boron-containing reducing agent. [In Formula (1), k represents 1 or 2; m and n each represents a number of 2-5; R represents a hydrogen atom, a halogen atom or the like; R1 represents an alkyl group having 1-6 carbon atoms; and R2 and R3 are combined with an adjacent nitrogen atom and form pyrrolidine, morpholine, thiomorpholine or the like.] [In Formula (3), R4 represents an alkyl group having 1-3 carbon atoms.]