| 摘要 |
PROBLEM TO BE SOLVED: To provide a composition and a method which can be utilized for wide variety of ligand pair reactions in which separation of target molecules based on size is required. SOLUTION: A compound is represented by the formula: T<SP>ms</SP>-L-X, wherein T<SP>ms</SP>is an organic group which is detectable by mass spectrometry and contains carbon, at least one of hydrogen and fluoride and optional atoms selected from oxygen, nitrogen, sulfur, phosphorus and iodine; L is an organic group which allows a unique T<SP>ms</SP>-containing moiety to be cleaved from the remainder of the compound, wherein the T<SP>ms</SP>-containing moiety comprises a functional group which supports a single ionized charge state when the compound is subjected to mass spectrometry and is tertiary amine, quaternary amine or organic acid; and X is a functional group selected from phosphoramidite and H-phosphonate. COPYRIGHT: (C)2009,JPO&INPIT
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