发明名称 |
Increased Bacterial CoA and Acetyl-CoA Pools |
摘要 |
Methods of increasing the cellular pool of A-CoA and thus driving the metabolic pathways in the direction of A-CoA containing metabolites by overexpressing rate limiting enzymes in A-CoA synthesis. Methods of increasing intracellular levels of CoA and A-CoA through genetic engineering of bacterial strains in conjunction with supplementation with precursor molecules.
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申请公布号 |
US2009186398(A1) |
申请公布日期 |
2009.07.23 |
申请号 |
US20080340349 |
申请日期 |
2008.12.19 |
申请人 |
RICE UNIVERSITY |
发明人 |
SAN KA-YIU;BENNETT GEORGE NELSON;VADALI RAVISHANKAR V. |
分类号 |
C12N1/20;C12N9/02;C12N9/12;C12P1/00;C12P7/62 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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