发明名称 |
METHODS AND TOOLS FOR THE SCREENING OF FACTORS AFFECTING PROTEIN MISFOLDING |
摘要 |
The present invention relates in general to the fields of chemical, pharmaceutical and genetic screening and to diseases associated with protein misfolding. In particular, it discloses engineered cells and a system based thereon that can be used to screen for substances that affect protein misfolding. The engineered cells of the invention comprise one or more reporter genes under transcriptional control of a promoter that is responsive to protein misfolding. |
申请公布号 |
US2009186354(A1) |
申请公布日期 |
2009.07.23 |
申请号 |
US20070303133 |
申请日期 |
2007.06.01 |
申请人 |
NV REMYND |
发明人 |
GRIFFIOEN GERARD;COUPET KRISTEL MARIE EDITH;VAN DAMME NELE;WERA STEFAAN |
分类号 |
C12N15/63;C12N1/19;C12Q1/68 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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