OIL AND LIQUID SILICONE FOAMABLE CARRIERS AND FORMULATIONS
摘要
A waterless foamable pharmaceutical composition suitable for external administration is disclosed. The composition includes a foamable carrier least one liquefied or compressed gas propellant. The foamable carrier includes at least one liquid oil; at least one silicone and at least one least one stabilizing agent; wherein the stabilizing agent selected from the group consisting of about 0.01 % to about 25% by weight of at least one surface-active agent alone or on combination with a foam adjuvant; and about 0% to about 5% by weight of at least one polymeric agent alone or on combination with a foam adjuvant; and mixtures thereof. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.
申请公布号
WO2009090495(A2)
申请公布日期
2009.07.23
申请号
WO2008IB03939
申请日期
2008.12.08
申请人
FOAMIX LTD.;TAMARKIN, DOV;SHIFRIN, HELEN;KEYNAN, RITA;ZIV, ENBAL;BERMAN, TAL;SCHUZ, DAVID
发明人
TAMARKIN, DOV;SHIFRIN, HELEN;KEYNAN, RITA;ZIV, ENBAL;BERMAN, TAL;SCHUZ, DAVID