| 发明名称 |
THERAPEUTIC COMPOUNDS |
| 摘要 |
<p>The invention provides compounds of formula I: wherein A, B, D, E, R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4</SUB>, R<SUB>5</SUB>, X, and ----- have any values defined herein, as well as salts thereof. The compounds have activity as G-quadruplex DNA stabalizers and as anti-proliferative agents.</p> |
| 申请公布号 |
EP2079704(A2) |
申请公布日期 |
2009.07.22 |
| 申请号 |
EP20070755933 |
申请日期 |
2007.04.24 |
| 申请人 |
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY;LAVOIE, EDMOND J.;RICE, JOSEPH E.;LIU, LEROY FONG |
发明人 |
LAVOIE, EDMOND, J.;RICE, JOSEPH, E.;LIU, LEROY, F. |
| 分类号 |
C07D498/22;A61K31/424;A61P35/00;C07D513/22;C07D515/22 |
主分类号 |
C07D498/22 |
| 代理机构 |
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| 主权项 |
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| 地址 |
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