发明名称 |
An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
摘要 |
An isolated nucleic acid is disclosed which comprises a nucleic acid sequence encoding a heavy chain of an antibody, wherein the heavy chain of the antibody comprises (i) SEQ ID NO:25 or a functional equivalent thereof, (ii) SEQ ID NO:26 or a functional equivalent thereof, and (iii) SEQ ID NO:27 or a functional equivalent thereof. |
申请公布号 |
EP2065400(A3) |
申请公布日期 |
2009.07.22 |
申请号 |
EP20080021291 |
申请日期 |
2001.05.02 |
申请人 |
UAB RESEARCH FOUNDATION |
发明人 |
ZHOU, TONG;ICHIKAWA, KIMIHISA;KIMBERLY, ROBERT P.;KOOPMAN, WILLIAM J. |
分类号 |
C07K16/00;C12N15/02;A01N43/04;A61K31/337;A61K39/395;A61K45/06;A61P1/04;A61P3/10;A61P5/18;A61P7/06;A61P9/10;A61P13/12;A61P15/00;A61P17/00;A61P21/04;A61P25/00;A61P29/00;A61P35/00;A61P37/08;A61P43/00;C07D305/14;C07H21/02;C07K16/28;C07K16/30;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N5/10;C12N15/00;C12N15/09;C12P21/08 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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