发明名称 DENDRITIC CELL CO-STIMULATORY MOLECULES
摘要 A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.
申请公布号 EP1280900(B1) 申请公布日期 2009.07.22
申请号 EP20010928894 申请日期 2001.04.27
申请人 THE JOHNS HOPKINS UNIVERSITY 发明人 PARDOLL, DREW, M.;TSUCHIYA, HARUO;GORSKI, KEVIN, S.;TSENG, SU-YI
分类号 C12N15/09;C12N15/12;A61K35/12;A61K35/14;A61K35/76;A61K38/00;A61K38/17;A61K39/00;A61K39/39;A61K39/395;A61K48/00;A61P35/00;A61P37/04;A61P37/06;C07K14/705;C07K14/725;C07K16/28;C07K19/00;C12N5/10;C12N15/62;C12P21/08 主分类号 C12N15/09
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