| 发明名称 |
Oligonucleotide conjugates |
| 摘要 |
Oligonucleotide conjugates, where an oligonucleotide is covalently attached to an aromatic system, are provided. In particular embodiments the oligonucleotide is complementary to the RNA component of human telomerase and is covalently attached to a nucleobase via an optional linker. The conjugates inhibit telomerase enzyme activity.
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| 申请公布号 |
US7563618(B2) |
申请公布日期 |
2009.07.21 |
| 申请号 |
US20020255535 |
申请日期 |
2002.09.25 |
| 申请人 |
GERON CORPORATION |
发明人 |
GRYAZNOV SERGEI;PONGRACZ KRISZTINA;TOLMAN RICHARD L.;MORIN GREGG B. |
| 分类号 |
C12Q1/68;A01N43/04;C07H21/00;C07H21/02;C07H21/04;C12N5/00 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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