| 发明名称 |
Recombinant chimeric human anti-botulinum antibodies |
| 摘要 |
In this application is described the production of recombinant, chimeric, humanized antibodies specific for both BoNt/A and BoNT/B. The humanized antibodies were converted from a mouse anti-BoNT/A/B Fab fragment into a whole human IgG1 antibody. The antibodies are useful in assays for detecting human exposure to BoNT/A and BoNT/B.
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| 申请公布号 |
US7563875(B2) |
申请公布日期 |
2009.07.21 |
| 申请号 |
US20060384712 |
申请日期 |
2006.03.20 |
| 申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SERCRETARY OF THE ARMY |
发明人 |
PALYS THOMAS J.;SCHOEPP RANDAL J.;SCHMID KARA E. |
| 分类号 |
C12P21/08;G01N33/577 |
主分类号 |
C12P21/08 |
| 代理机构 |
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