| 发明名称 |
Removal of aldehyde impurity by reactive polystyrene resini |
| 摘要 |
A purification method in the preparation of a substituted 8-arylquinoline, wherein the aryl group at the 8-position contains a substituent substituted-alkenyl group, utilizes a polystyrene-based sulfonylhydrazine reactive resin to remove an aldehyde impurity.
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| 申请公布号 |
US7563807(B2) |
申请公布日期 |
2009.07.21 |
| 申请号 |
US20030526782 |
申请日期 |
2003.09.12 |
| 申请人 |
MERCK & CO. INC. |
发明人 |
BIBA MIRLINDA;COLLINS PAUL COMPTON;WELCH CHRISTOPHER JOSEPH;CONLON DAVID A.;DRAHUS ANTOINETTE |
| 分类号 |
A61K31/47;A61K31/4709;C07D215/14;C07D401/10;C07D413/10 |
主分类号 |
A61K31/47 |
| 代理机构 |
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